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Although no major discrepancies have been found in tyrosine hydroxylase action and expression, brain tissue amounts of 3,four-dihydroxyphenylalanine ended up threefold greater in α2A- and α2C-adrenoceptor KO mice. Mind tissue levels of dopamine and noradrenaline were being drastically greater in α2A and α2CKOs compared with WT [WT: two.The fina